How do I fit multiple curves at once, sharing some fitting parameters and floating others?
Hi,
I am new to using MATLAB and SIMBIOLOGY. I am trying to fit 6 binding curves where the ligand is the same throughout the experiment and only the analyte concentrations are different. I want to globally fit all 6 curves to one model, sharing the rate parameters but not sharing the concentration parameters. Is there a way to do this in simbiology? When I am setting up the Data Map I have my independent variable as Time, since binding is measured over time, and I have 6 responses each corresponding to my binding response generated for each analyte concentration. I get an error of "The same model component appears in the left-hand side of multiple elements of the responseMap input argument. The responseMap cannot contain any duplicates." Any help would be great! Attached is the data I am trying to fit.Hi,
I am new to using MATLAB and SIMBIOLOGY. I am trying to fit 6 binding curves where the ligand is the same throughout the experiment and only the analyte concentrations are different. I want to globally fit all 6 curves to one model, sharing the rate parameters but not sharing the concentration parameters. Is there a way to do this in simbiology? When I am setting up the Data Map I have my independent variable as Time, since binding is measured over time, and I have 6 responses each corresponding to my binding response generated for each analyte concentration. I get an error of "The same model component appears in the left-hand side of multiple elements of the responseMap input argument. The responseMap cannot contain any duplicates." Any help would be great! Attached is the data I am trying to fit. Hi,
I am new to using MATLAB and SIMBIOLOGY. I am trying to fit 6 binding curves where the ligand is the same throughout the experiment and only the analyte concentrations are different. I want to globally fit all 6 curves to one model, sharing the rate parameters but not sharing the concentration parameters. Is there a way to do this in simbiology? When I am setting up the Data Map I have my independent variable as Time, since binding is measured over time, and I have 6 responses each corresponding to my binding response generated for each analyte concentration. I get an error of "The same model component appears in the left-hand side of multiple elements of the responseMap input argument. The responseMap cannot contain any duplicates." Any help would be great! Attached is the data I am trying to fit. curve fitting, simbiology, binding, multiple curves MATLAB Answers — New Questions
